Researcher at CNRS
LIMMS/CNRS-IIS, The University of Tokyo, Lille, France
Jean-Claude GERBEDOEN was born in Bailleul, France in 1981. He received the PhD degree from the Université des Sciences et Technologies de Lille and Institut d’Electronique, de Microélectronique et de Nanotechnologie (IEMN), in 2009 in Micro and Nanotechnology, Acoustic, Telecommunication in the field of wide bandgap power transistors. Then, he did several post-doctoral fellow in France and at Sherbrooke University (Canada). He worked on different topics as power transistors for hybrid vehicles, UV LEDs for skin treatment, MEMS devices for aerodynamic flow control on vehicle to enhance the aerodynamic drag. From 2016, he worked for SATT NORD in 3-years maturation project concerning the development of acoustic tweezers for alive cells manipulation in microfluidic devices. Since 2019, he joined the SMMIL-E project as clean room manager and he is actively involved in MEMS fabrication for cancer research.
- 2009 PhD, Micro and Nano Technology, Acoustic, Telecommunication, Doctoral School, University of Lille, Lille, France.
- 2005 Advanced study degree (DEA) in Micro and Nanotechnology, University of Lille, France
- 2004 Professional master (DESS) in Microelectronic, Radiofrequency and Hyperfrequency, University of Lille, France.
- 2019-present Clean Room Manager in SMMIL-E team, CNRS researcher, IRCL, Lille, France
- 2016-2019 Development Engineer, SATT NORD, University of Lille, France
- 2015-2016 Teaching assistant, Ecole Centrale de Lille, France
- 2012-2015 Post-doctoral research fellow, IEMN, University of Lille, France
- 2011-2012 Post-doctoral research fellow, IEMN, University of Lille, France.
- 2009-2011 Post-doctoral research fellow, Faculty of Engineering, University of Sherbrooke, Sherbrooke, Québec, CANADA
SELECTED ONGOING PROJECTS
- Distinguishing cancer cells based on their biophysical signatures
Changes in cell shape and structural integrity affect many biological processes related to cells. Therefore, we can potentially use the biophysical properties of cells to reflect the state of their health. This connection between the biophysics and diseases has been attracting scientific research attention, especially for cancer research, where diseased cells proliferate uncontrollably and disrupt the organization of tissue. Here, we target a reliable and practical high-throughput technique to obtain the biophysical signature of cancer cells. We take two parallel approaches to achieve this goal. We use MEMS grippers (i.e., Silicon NanoTweezers) that provide higher sensitivity to examine different biophysical properties (e.g., size, stiffness, viscosity, and electrical properties). In parallel, we are developing a high-throughput MEMS device optimized according to the SNT results for clinical applications.
SELECTED PUBLICATIONS (on cells)
- Rezard Q, Perret G, Gerbedoen J-C, Pekin D, Cleri F, Collard D, Lagadec C, Tarhan MC. Developing A Mems Device for High-Throughput Multi-Parameter Single Cell Biophysical Analysis. 2021 IEEE 34th International Conference on Micro Electro Mechanical Systems (MEMS), 2021, pp. 494-497.
- Baudoin M, Thomas J-L, Al Sahely R , Gerbedoen J-C , Gong Z, Sivery A, Bou Matar O, Smagin N, Favreau P, Vlandas A. Spatially selective manipulation of cells with single-beam acoustical tweezers. Nature Communications (2020) 11, 4244.
- Pekin D, Perret G, Rezard Q, Gerbedoen J-C, Meignan S, Collard D, Lagadec C, Tarhan M.C. Subcellular Imaging During Single Cell Mechanical Characterization. 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS), 2020, pp. 62-65.